Saturday, June 14, 2014

Epiglottitis

 
Acutely inflamed epiglottis associated with Haemophilus influenza type B


Definition

Epiglottitis is a rapidly progressive cellulitis of the epiglottis and adjacent soft tissue structures with the potential to cause abrupt airway obstruction.

Physical finding and Clinical presentation
  • Irritability, fever, dysphonia, dysphagia
  • Respiratory distress, with child tending to lean up and forward
  • Often, drooling or oral secretions
  • Often, presence of tachycardia and tachypnea
  • On visualization, edematous and cherry red epiglottis
  • Often, no classic barking cough as seen in croup
  • Possibly fulminant course (especially in children), leading to complete airway obstruction.
Cause
  • In children, Haemophilus infl uenzae type B is usual.
  • In adults, H. infl uenzae can be isolated from blood, epiglottis (about 26% of cases), or both.
  • Pneumococci, streptococci, and staphylococci are also implicated.
  • Role of viruses in epiglottitis unclear.
Differential Diagnosis
  • Croup
  • Angioedema
  • Peritonsillar abscess
  • Retropharyngeal abscess
  • Diphtheria
  • Foreign body aspiration
  • Lingual tonsillitis
Work Up
  • Cultures of blood and urine
  • Lateral neck radiograph to show an enlarged epiglottis, ballooning of the hypopharynx, and normal subglottic structures
    • Radiographs are of only moderate sensitivity and specificity and take time to perform.
    • Visualization of the epiglottitis may be safer in adults than in children. In children, visualization and intubation are best done in the most controlled environment.
  • Cultures of the epiglottitis
Laboratory Tests
  • CBC: may reveal a leukocytosis, with a shift to the left
  • Chest x-ray examination: may reveal evidence of pneumonia in almost 25% of cases
  • Cultures of blood, urine, and epiglottis, as noted
Treatment
  • Maintenance of adequate airway is critical.
  • Early placement of an endotracheal or nasotracheal tube in a child is advised.
  • Closely follow adult patient and defer intubation, provided the airway reveals no signs of obstruction.
  • H. influenzae in children may be less common because of the availability of the Hib vaccine.
  • Use antibiotics such as ceftriaxone, cefotaxime.
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